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cholecystokinin receptor br Conflict of interest br Introduc
2019-06-26
Conflict of interest Introduction Case report A 5-year-old boy was admitted for treatment of atrial flutter after correction of pulmonary atresia with ventricular septal defect. The patient had undergone total correction of cardiac disease at 4 years and 2 months of age after previous bilat
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Twenty six of the patients had an early discontinuation due
2019-06-26
Twenty-six of the 98 patients had an early discontinuation due to recurrence: there were 14 patients with distant MLN120B what and 12 with local recurrence. Most distant metastatic events (71.4%) occurred within the initial two years. Of the other 72 patients with early discontinuation of ET, only
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Among patients with established infection in the bone
2019-06-26
Among patients with established infection in the bone or surrounding tissue (Stage II) antibiotic penicillin-based therapy in addition to mouthwash may result in healing in patients with minor ONJ lesions. However, a large proportion of cases tend to show chronically infected necrotic process in jaw
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In the phase AZURE trial women were
2019-06-26
In the phase 3 AZURE trial, 3360 women were randomly assigned to receive standard adjuvant systemic treatment alone (control group) or with 4mg intravenous zoledronic PD 123319 ditrifluoroacetate every 3–4 weeks for 6 doses, then every 3 months for 8 doses, followed by every 6 months for 5 doses, fo
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Cerrone et al reported that the mechanism of
2019-06-26
Cerrone et al. reported that the mechanism of CPVT was due to delayed afterdepolarization‐induced triggered activity in a focal Purkinje network in a knock-in (RyR2) mouse [36]. In addition, chemical ablation of the RV endocardial cavity with Lugol׳s solution, which selectively destroys the Purkinje
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br Discussion This study shows that the risk of all
2019-06-26
Discussion This study shows that the risk of all-cause mortality in patients with atrial fibrillation is directly associated with RDW in a dose-response manner. This association was independent of known risk factors of mortality. Notably, RDW is associated with all-cause mortality regardless of a
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I am delighted to introduce the inaugural
2019-06-26
I am delighted to introduce the inaugural issue of . It is very likely that you are reading this online, this being an online-only journal, although we have also printed this first issue in order to showcase the journal to readers of . What is certain is that, in accessing this article, and all the
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There are major challenges in the estimation of the prevalen
2019-06-26
There are major challenges in the estimation of the prevalence of opioid use in Afghanistan. The country has been in a state of war and insurgency for the better part of 40 years; its LEE011 is widely dispersed and often very mobile; it has low levels of literacy; and Afghans are not accustomed to a
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The clinical spectrum of intracranial hemorrhage is similar
2019-06-25
The clinical spectrum of intracranial hemorrhage is similar for patients treated with warfarin and dabigatran [10]. Absolute rates of intracranial hemorrhage across all sites and of both fatal and traumatic intracranial hemorrhages are lower with dabigatran than with warfarin [10]. Concomitant aspir
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Patients with heart failure are at a high
2019-06-25
Patients with heart failure are at a high risk of mortality and morbidity. Medical expenses associated with heart failure are increasing, and approaches aimed at early heart failure detection and reduction of the hospitalization rate are yet to be developed. Patients with CIEDs also develop heart fa
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In the current era nearly all cases of hormone receptor
2019-06-25
In the current era, nearly all cases of hormone-receptor positive breast cancer are treated with adjuvant endocrine therapy irrespective of staging, with preference for aromatase inhibitors over tamoxifen because of side effect profile, survival outcome and tumor recurrence rates [4,11]. In our stud
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Tentativas de encontros frequentes os debates
2019-06-25
Tentativas de encontros frequentes, os debates e as polêmicas contribuem para Famprofazone consolidação efetiva de um projeto coletivo em torno dos objetivos editoriais e políticos de uma revista. No caso de Araucaria de Chile, no que concerne às representações sobre as revoluções cubana e sandinist
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In summary we present a rare case
2019-06-25
In summary, we present a rare case of magnesium sulfate-induced fetal bradyarrhythmia caused by prolongation of the refractory period of the atrioventricular node in the case of blocked premature atrial contractions. Clinicians should consider fetal bradyarrhythmia when the baseline fetal heart rate
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Introduction Researchers have long followed the strategy
2019-06-25
Introduction Researchers have long followed the strategy that in order to achieve a fuller understanding of the causes of disease and how they can be prevented, it is necessary to study the biochemical and physiological processes involved in the etiology of disease. As I have argued in previous pap
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br Conflict of Interest br Acknowledgments br
2019-06-25
Conflict of Interest Acknowledgments Introduction Human ether-a-go-go-related gene (hERG) encodes the alpha subunit of the rapidly-activating delayed-rectifier K+ channel, which plays a pivotal role in repolarization of cardiac action potentials (APs) [1]. Most of mutant hERG proteins causi
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