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Different types of environmentally induced antinociception h
2020-05-14
Different types of environmentally induced antinociception have been reported in a wide range of species (e.g., Behbehani, 1995, Bolles and Fanselow, 1980, Harris, 1996, Millan, 2002, Rodgers, 1995). According to Bolles and Fanselow (1980), fear and pain are independent and competing motivational sy
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Conventional configurations for alkanolamine and
2020-05-14
Conventional configurations for alkanolamine and 1,4-DPCA sale gas are not suitable to represent the chemical reaction between acid gas and alkanolamines. Nevertheless, Dowell et al. [17] have successfully represented the phase behaviour of CO2-water-MEA systems by using SAFT-VR [18] without any con
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Hence what is proposed here is a
2020-05-14
Hence, what is proposed here is a technique highly used in reliability engineering: Software Rejuvenation[4], [21], a technique of proactive fault tolerance in which the system is periodically reboot to clean the memory. In fact, it is well known that most critical SW failures are transient. These m
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br Introduction The dopaminergic system and its projections
2020-05-14
Introduction The dopaminergic system and its projections including both the prefrontal Amyloid β-peptide (10-35), amide (PFC) and striatum are known as being crucial to synaptic plasticity, skill acquisition and higher order functions (e.g., working memory and cognitive control; Matsumoto et al.
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br Acknowledgements We thank A
2020-05-14
Acknowledgements We thank A. Devia-Barros and S.A. Barrios Latorre for invaluable technical support during the collection, maintenance and exposure of oysters. We are, furthermore, grateful to the municipal marina of Santa Marta for authorizing access to their facilities and to A. Franco for faci
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br Acknowledgements br Introduction Water and
2020-05-14
Acknowledgements Introduction Water and electrolytes constitute an integral part of all living things, and CJ-42794 governing their movements play important roles in a wide variety of physiological and/or pathophysiological processes. Given the importance of channel proteins in cancer cell pr
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br Acknowledgements This study was financially supported by
2020-05-14
Acknowledgements This study was financially supported by the National Special Research Programs for Non-Profit Trades (Agriculture) (Grant No. 201303045) and the Basic Foundation for Scientific Research of the State-level Public Welfare Institutes of China (Grant No. 2013JB10). Introduction L
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Despite robust translation of GA only small amounts of GR
2020-05-14
Despite robust translation of GA, only small amounts of GR and GP were translated in cultured dna methyltransferase and chick embryo spinal cord neural cells from the 75 copies of G4C2 in monocistronic constructs. Interestingly, GA is also the most common dipeptide found in autopsy tissue in FALS p
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We propose the following model for how B cell
2020-05-14
We propose the following model for how B cell-guiding EBI2 ligand gradients are established in lymphoid tissues. CH25H and CYP7B1 are needed in radiation-resistant stromal cells, are abundantly expressed and active in CXCL13+ and CCL21+ FRCs, but not lymphocytes, and are poorly expressed in the inne
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The RING domain was previously considered sufficient to
2020-05-14
The RING domain was previously considered sufficient to confer ubiquitination by RING-type E3 ligases. However, recent reports have shown that sequences closest to the RING domain are also important in E3 ligase function. Residues like Tyr193 in RNF4 [40], Phe296 and Arg294 in BIRC7 [31], and Lys65
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The synthesis of compounds a
2020-05-14
The synthesis of compounds 7a and 7b are outlined in Scheme 2. Compound 5 was obtained by di-tert-butyl pyrocarbonate protection of Immunology Compound Library 4a. Then, compounds 6a and 6b were obtained by amination of the fluoride with a morpholino and dimethylamine, respectively. Target compounds
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CellProfiler and OpenComet are two open source software
2020-05-14
CellProfiler and OpenComet are two open source software available in internet to analyse silver stained comet assay images. With CellProfiler [19], Gonzalez et al. [18] modified the pipeline provided in the website by adding a background subtraction module and two filtering modules to quantify DNA d
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br Acknowledgments Studies in the Tomkinson laboratory on DN
2020-05-14
Acknowledgments Studies in the Tomkinson laboratory on DNA ligase III are supported by research grants from the National Institutes of Health (P01 CA92584 and ES12512 to AET), a grant from the V Foundation and the University of New Mexico Cancer Center. Introduction Ionizing radiation (IR) as
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br Material and methods br Results
2020-05-14
Material and methods Results Discussion Ligase IV is essential for the final ligation of DSBs through the NHEJ pathway. Its co-factor, XRCC4, has been shown to be important for increasing its activity and stability. Interaction between these two factors have been mapped to the linker region
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br Acknowledgments We thank Jon Clardy Juan Manuel Dom nguez
2020-05-14
Acknowledgments We thank Jon Clardy, Juan Manuel Domínguez, José Francisco García Bustos, and the GlaxoSmithKline (GSK) Plasmodium falciparum dihydroorotate dehydrogenase project team for their contributions, helpful advice, and discussions. Introduction Dihydroorotate dehydrogenase (DHODH) i
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